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 Indian J Med Microbiol  
 

Figure 3: Down-regulated common DEGs of two datasets GSE44777, GSE6053 (Group 2). (a) Heat map (The fold change expression of genes are displayed in ascending order from blue to red colour) of common dDown-regulated common DEGs; (b) Violin plot shown the distribution of common dDown-regulated common DEGs (Yoga: Red colour, Exercise: Blue colour); (c) OMIM Disease (Gene-Disease Interaction of Group 2); (d) KEGG pathway (e) CC; (f) BP; (g) MF; (h) PPI network, (0.47 nodes, 37 edges, and PPI enrichment P = 0.0317 at medium confidence [0.400]). Identified 16 Hub genes (Pink Colour) BCL2, CD160, CD69, DDIT4, ESR1, FARSA, FKBP5, IDH2, KLHL3, LDLR, NUP107, PRDM1, SIRT3, SOCS1, and TSEN2 in the PPI network. CD160 = CD160 molecule, CD69 = CD69 molecule, DEGs = Differentially expressed genes, BP = Biological process, CC = Cellular components, MF = Molecular function, PPI = Protein-protein interaction, Bcl-2 = Bcl-2 apoptosis regulator, DDIT4 = DNA damage inducible transcript 4, ESR1 = Estrogen receptor 1, FARSA = Phenylalanyl-tRNA synthetase subunit alpha, FKBP5 = FKBP prolyl isomerase 5, IDH2 = Isocitrate dehydrogenase (NADP[+]) 2, KLHL3 = Kelch like family member 3, LDLR = Low density lipoprotein receptor, NUP107 = Nucleoporin 107, PRDM1 = PR/SET domain 1, SIRT3 = Sirtuin 3, SOCS1 = Suppressor of cytokine signaling 1, TSEN2 = tRNA splicing endonuclease subunit 2

Figure 3: Down-regulated common DEGs of two datasets GSE44777, GSE6053 (Group 2). (a) Heat map (The fold change expression of genes are displayed in ascending order from blue to red colour) of common dDown-regulated common DEGs; (b) Violin plot shown the distribution of common dDown-regulated common DEGs (Yoga: Red colour, Exercise: Blue colour); (c) OMIM Disease (Gene-Disease Interaction of Group 2); (d) KEGG pathway (e) CC; (f) BP; (g) MF; (h) PPI network, (0.47 nodes, 37 edges, and PPI enrichment <i>P</i> = 0.0317 at medium confidence [0.400]). Identified 16 Hub genes (Pink Colour) BCL2, CD160, CD69, DDIT4, ESR1, FARSA, FKBP5, IDH2, KLHL3, LDLR, NUP107, PRDM1, SIRT3, SOCS1, and TSEN2 in the PPI network. CD160 = CD160 molecule, CD69 = CD69 molecule, DEGs = Differentially expressed genes, BP = Biological process, CC = Cellular components, MF = Molecular function, PPI = Protein-protein interaction, Bcl-2 = Bcl-2 apoptosis regulator, DDIT4 = DNA damage inducible transcript 4, ESR1 = Estrogen receptor 1, FARSA = Phenylalanyl-tRNA synthetase subunit alpha, FKBP5 = FKBP prolyl isomerase 5, IDH2 = Isocitrate dehydrogenase (NADP[+]) 2, KLHL3 = Kelch like family member 3, LDLR = Low density lipoprotein receptor, NUP107 = Nucleoporin 107, PRDM1 = PR/SET domain 1, SIRT3 = Sirtuin 3, SOCS1 = Suppressor of cytokine signaling 1, TSEN2 = tRNA splicing endonuclease subunit 2