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 Indian J Med Microbiol  
 

Figure 4: Exercise up-regulated and yoga down-regulated common DEGs of two datasets GSE44777, GSE6053 (Group 3). (a) Heat map (The fold change expression of genes are displayed in ascending order from blue to red colour) of Exercise up-regulated and yoga down-regulated common DEGs; (b) Violin plot shown the entire FCE distribution violin plot of exercise up-regulated and Yoga down-regulated of common DEGs (Yoga: Red colour, Exercise: Blue colour); (c) OMIM disease (gene-disease interaction of group 2); (d) KEGG pathway (e) CC; (f) BP; (g) MF; (h) PPI network (The 16 nodes, 19 edges, and PPI enrichment P = 0.000 at medium confidence [0.400]) identified 5 hub genes (Pink colour) GABRB3, GRM5, PRKCA, SLC17A7, in the PPI network. DEGs = Differentially expressed genes, BP = Biological process, CC = Cellular components, MF = Molecular function, PPI = Protein-protein interaction, GRM5 = Glutamate metabotropic receptor 5, PRKCA = Protein kinase C alpha, SLC17A7 = Solute carrier family 17 member 7, EPHA1 = EPH receptor A1, GABRB3 = Gamma-aminobutyric acid type A receptor subunit beta 3

Figure 4: Exercise up-regulated and yoga down-regulated common DEGs of two datasets GSE44777, GSE6053 (Group 3). (a) Heat map (The fold change expression of genes are displayed in ascending order from blue to red colour) of Exercise up-regulated and yoga down-regulated common DEGs; (b) Violin plot shown the entire FCE distribution violin plot of exercise up-regulated and Yoga down-regulated of common DEGs (Yoga: Red colour, Exercise: Blue colour); (c) OMIM disease (gene-disease interaction of group 2); (d) KEGG pathway (e) CC; (f) BP; (g) MF; (h) PPI network (The 16 nodes, 19 edges, and PPI enrichment <i>P</i> = 0.000 at medium confidence [0.400]) identified 5 hub genes (Pink colour) GABRB3, GRM5, PRKCA, SLC17A7, in the PPI network. DEGs = Differentially expressed genes, BP = Biological process, CC = Cellular components, MF = Molecular function, PPI = Protein-protein interaction, GRM5 = Glutamate metabotropic receptor 5, PRKCA = Protein kinase C alpha, SLC17A7 = Solute carrier family 17 member 7, EPHA1 = EPH receptor A1, GABRB3 = Gamma-aminobutyric acid type A receptor subunit beta 3